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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM5A
All Species:
12.42
Human Site:
S1666
Identified Species:
30.37
UniProt:
P29375
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29375
NP_001036068.1
1690
192095
S1666
A
K
K
Q
G
P
V
S
P
G
P
A
P
P
P
Chimpanzee
Pan troglodytes
Q5XUN4
1535
173724
S1512
N
S
L
Q
H
K
D
S
G
S
S
A
A
C
P
Rhesus Macaque
Macaca mulatta
XP_001090508
1411
159177
L1388
L
T
G
P
V
L
E
L
P
E
A
T
R
A
P
Dog
Lupus familis
XP_854690
1767
200598
S1743
A
K
K
Q
G
P
D
S
P
G
Q
A
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UXZ9
1690
192198
S1666
A
K
K
Q
G
P
D
S
P
G
Q
A
P
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508780
1538
174757
C1511
N
Q
W
F
H
Q
V
C
V
G
V
S
P
E
M
Chicken
Gallus gallus
Q5F3R2
1522
173443
S1499
H
Q
V
C
V
G
I
S
P
E
M
A
E
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQX0
1503
171080
S1480
H
M
I
C
V
G
V
S
A
E
L
A
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMJ7
1838
203974
T1813
T
K
T
V
A
I
G
T
Q
G
S
G
H
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23541
1477
170773
D1454
F
T
L
R
E
I
N
D
M
H
E
Y
R
C
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
48.9
93
N.A.
96.6
N.A.
N.A.
50.2
50.3
N.A.
46.6
N.A.
37.3
N.A.
28.5
N.A.
Protein Similarity:
100
65.5
61.7
94
N.A.
98.6
N.A.
N.A.
67
66.6
N.A.
63.9
N.A.
52.3
N.A.
48.4
N.A.
P-Site Identity:
100
26.6
13.3
86.6
N.A.
86.6
N.A.
N.A.
20
20
N.A.
20
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
26.6
13.3
86.6
N.A.
86.6
N.A.
N.A.
33.3
33.3
N.A.
20
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
10
0
0
0
10
0
10
60
20
10
0
% A
% Cys:
0
0
0
20
0
0
0
10
0
0
0
0
0
20
0
% C
% Asp:
0
0
0
0
0
0
30
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
30
10
0
10
20
20
% E
% Phe:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
30
20
10
0
10
50
0
10
0
0
0
% G
% His:
20
0
0
0
20
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
20
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
40
30
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
20
0
0
10
0
10
0
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
20
% M
% Asn:
20
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
30
0
0
50
0
10
0
40
30
50
% P
% Gln:
0
20
0
40
0
10
0
0
10
0
20
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
20
0
0
% R
% Ser:
0
10
0
0
0
0
0
60
0
10
20
10
0
10
10
% S
% Thr:
10
20
10
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
10
10
30
0
30
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _